Reperfusion Injury,Myocardial

《英文msh詞典》Reperfusion Injury,Myocardial
[同義詞] Reperfusion Injury,Myocardial
[主題詞] Myocardial Reperfusion Injury
[中文釋義] 再灌流損傷,心肌
[英文釋義] Functional,metabolic,or structural changes in ischemic heart muscle thought to result from REPERFUSION to the ischemic areas. Changes can be fatal to muscle cells and may include edema with explosive cell swelling and disintegration,sarcolemma disruption,fragmentation of mitochondria,contraction band necrosis,enzyme washout,and calcium overload. Other damage may include hemorrhage and ventricular arrhythmias. One possible mechanism of damage is thought to be oxygen free radicals. Treatment currently includes the introduction of scavengers of oxygen free radicals,and injury is thought to be prevented by warm blood cardioplegic infusion prior to reperfusion.